The server lets users mutate proteins in various ways and study mutation effects in 3D. The only required inputs are a structural model and a list of mutations of interest. Alternatively, the user can upload human SNPs in the VCF format.
You can click on the buttons at each field in the forms to get further information.

Main steps


Or: Or: Always:

Structure upload

Structures can be uploaded in three different ways:

Define mutations

Mutations can be defined in three different ways:

Mutation syntax


You can select a model and further mutate this using the mutation window.

Expected time requirements

Actual times depend on the size of the system and may vary significantly.

Details can be found in the FAQs.